After you’ve just worked a full day at a stressful job, sitting on your couch, and remembering it’s only Monday is a soul-crushing experience. Advocates of shorter work weeks refer to numerous studies that demonstrate that the nine-to-five grind can not only have health implications but is not necessarily productive.

Hopefully, logic will eventually prevail and encourage more employers to implement more reasonable work schedules. But until then, from contractors to television personalities, the first thing many do when they get home from their nine-to-five job is to reach for their stash to decompress.

These strains, in particular, have the power to boost your mood, cure your sorrows and heal your soul:

1. Blue Dream

Blue Dream is a Sativa-dominant strain that combines the relaxing experience of the Indica-dominant Blueberry and the uplifting, mood-boosting properties of Sativa-dominant Haze. It’s no shocker then that the two leading effects of this strain are relaxation and happiness. It’s also known to target depression and stress.  So if you’re fed up with life in the East Coast urban meat-grinder, Blue Dream will give you a perfect dose of the laid-back West Coast lifestyle.

Allevi8 Blue Dream 39 If Your 9 to 5 is Crushing Your Soul, These Strains Will Cure Your Stress

2. Pineapple Express

Yes, it’s a real strain. And yes, it’s incredible. Pineapple Express, a cross between the hybrid Trainwreck and Sativa-dominant Hawaiian, is a go-to strain for those experiencing depression. If you use Pineapple Express, you should expect to get an instant uptick in mood—the strain’s prominent effects are happiness and uplifting euphoria. Just like Blue Dream, this strain is also fantastic for treating stress and depression. In fact, the only downside to Pineapple Express is the possibility of cotton mouth. With consistently fantastic reviews from users, Pineapple Express has the added novelty of being the weed that sparked a Seth Rogen blockbuster. In fact, you might just say this is “the dopest dope” you’ll ever smoke.

Pineapple If Your 9 to 5 is Crushing Your Soul, These Strains Will Cure Your Stress

3. Blue Diesel

Remember when you first started smoking weed, and you couldn’t talk to a grocery store clerk or gas station attendant without bursting into an uncontrollable fit of giggles? If you’re looking to laugh, Blue Diesel is the strain for you. This strain is a cross between the Indica-dominant Blueberry and Sativa-dominant NYC Diesel. Users of this strain should expect a nice, relaxing body buzz without the “couch-locked” experience of other, heavy Indica strains. If you just got home from an important meeting only to discover you had a strand of spinach stuck in your teeth the whole time, you’ll want to take a puff of Blue Diesel. Laughter might be the best medicine, but Blue Diesel is the best medicine for laughter.

Atomic Congolese If Your 9 to 5 is Crushing Your Soul, These Strains Will Cure Your Stress

4. Durban Poison

If your nine-to-five job involves hard labor leaving you exhausted at the end of the day, Durban Poison is for you. This strain is renowned for its energy-boosting properties. This is probably due to the high level of THCV in Durban Poison, a cannabinoid that works to restore energy and offers a clear-headed, euphoric high that dissolves stress. Users of this strain often compare it to drinking a strong cup of coffee. So if you’ve been drinking coffee all day to get you through work, and you don’t want any more caffeine in your system, this strain will keep you going throughout the afternoon. The top effects of Durban Poison are a surge in energy and uplifted mood.

BC Sweet Tooth If Your 9 to 5 is Crushing Your Soul, These Strains Will Cure Your Stress

5. Laughing Buddha

If you’re looking for a practitioner to cure your spiritual fatigue, who better than the Buddha of weed strains? This strain is another excellent choice for those looking to indulge in non-stop laughter. The Laughing Buddha is a Sativa-dominant strain and winner of the 2003 High Times Cannabis Cup. Its parent strains are the Sativa-dominant Thai and Jamaican. The Laughing Buddha has a euphoric effect that will leave users feeling giggly and carefree. If your nine-to-five job is crushing your soul, killing your vibe and making you wonder what it’s all worth, you’ll be hard-pressed to find a better therapist than the Laughing Buddha.

Traphouse Black Berry Kush 2 If Your 9 to 5 is Crushing Your Soul, These Strains Will Cure Your Stress