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Most people know that THC is the active agent that gets you high, but few of us know much beyond that. What’s CB1? Endocannabinoid?! Read on to find out how THC interacts with your body,and learn some fun facts to wow your friends.

 How Cannabinoids Interact with the Body

How Cannabinoids Interact with the Body

By The Stoner's Cookbook

Most of us know that THC is the active agent that gets us high. But how does it work? We broke down norml.org's article on the basics.

  • Overview

    By The Stoner's Cookbook

    We experience a high after ingesting cannabis because cannabinoids interact with a receptor system within the body. THC is the cannabinoid in marijuana that's famous for its psychological effects.

  • Endocannabinoids

    By The Stoner's Cookbook

    Endocannabinoids naturally occur in humans & have similar molecular structure to herbal cannabinoids. They regulate many essential physiological functions like appetite, pain sensation & memory.

  • CB1 Receptors

    By The Stoner's Cookbook

    CB1 receptors reside mostly in the nervous system. Their stimulation is responsible for psychoactive & behavioral effects, among other functions.

  • CB2 Receptors

    By The Stoner's Cookbook

    CB2 receptors reside primarily in the immune system and are involved in the moderation of a number of biological functions, including inflammation and pain response.

  • How receptors & cannabinoids interact

    By The Stoner's Cookbook

    While CB1 & CB2 are primarily located in the nervous & immune system respectively, they can be found in most cells. When these receptors are stimulated, we notice a change in feeling or behavior.

  • Diseases

    By The Stoner's Cookbook

    It's theorized that a properly functioning endogenous cannabinoid receptor system is necessary for good health and that certain disease types may be the result of deficiencies within this system.

  • Effects

    By The Stoner's Cookbook

    Effects vary from subject to subject. Many of the plant's effects are dependent on percentage of THC and other cannabinoids (such as CBD, which counteracts THC) present in the cannabis consumed.

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