List of Weed Shops in Orlando, Florida

Orlando may be best known for its theme parks, but it’s also become one of Florida’s busiest medical cannabis hubs. Since voters approved medical marijuana in 2016, patients with qualifying conditions can legally access cannabis through tightly regulated Medical Marijuana Treatment Centers (MMTCs). Florida law requires that medical marijuana “may only be purchased from a licensed medical marijuana treatment center,” so every “weed shop” in this guide is a medical dispensary operating under that framework rather than a recreational pot shop. A 2024 constitutional amendment (Amendment 3) to legalize adult-use cannabis won a majority but failed to reach Florida’s 60% supermajority requirement, which means Orlando remains a medical-only market. Herb’s Orlando dispensary directory tracks who’s open, their hours, and what’s nearby, while Herb’s broader educational guides help patients understand product types and formats before they ever step into a shop. 

• Orlando is a medical-only cannabis market – Florida allows medical marijuana but still prohibits recreational sales, so all “weed shops” here are MMTC-licensed medical dispensaries serving registered patients only
• You must be in Florida’s medical program to buy cannabis – Patients need a valid Florida medical marijuana card and active state registry profile to make purchases; casual visitors without state registration can’t legally buy medical marijuana products from these state-licensed dispensaries in Orlando
• The city has a dense cluster of dispensaries – With more than 600 medical dispensaries scattered across Florida, Orlando stands out for its combination of tourist-area shops and neighborhood storefronts that show up prominently in Herb’s local listings
• Big brands and local favorites coexist – Trulieve, Curaleaf, MÜV, Sunnyside, Jungle Boys, Fluent, Cannabist, and VidaCann all maintain Orlando locations that appear in Herb’s directory, giving patients a wide range of product lines and store atmospheres to choose from.
• Herb helps compare options before you visit – You can use Herb’s dispensaries page and deals hub to see which Orlando shops are close by, what hours they keep, and what promotions they’re running on any given day.

Trulieve – Orlando South is one of the city’s most established medical dispensaries, serving patients on the busy South Orange Blossom Trail corridor. The shop reflects Trulieve’s broader Florida footprint, with a large, medical-focused layout and a wide menu ranging from traditional flower to capsules and tinctures. Inside, patient consultants move at a measured pace, explaining product formats and helping customers navigate different potencies and delivery methods without pressure. Because it sits near major commuter routes and residential neighborhoods, this location often functions as a primary “home base” dispensary for many Orlando patients that you’ll also see highlighted across Herb’s Florida coverage.

Trulieve emphasizes consistency, so regulars often rely on familiar formulations and brands across multiple visits. The Orlando South store also mirrors the company’s statewide loyalty and discount structure, which is helpful if you already shop at other Trulieve locations listed on Herb. While the atmosphere is clinical rather than flashy, it’s approachable for first-time patients who want a straightforward medical experience.

What Makes Them Special:

• Deep Florida footprint: Patients who travel within the state appreciate being able to find Trulieve locations in many cities, including multiple stores featured in Herb’s Orlando directory
• Large, medical-oriented menu: Flower, vapes, concentrates, capsules, edibles, and more under a single roof
• Regular discounts and loyalty perks: Rotating promotions for first-time patients, renewals, and returning customers
• Patient-focused service: Staff are used to answering questions from new patients who are still learning how different product types work

Best For: Registered Florida patients who value consistency, predictable inventory, and a clear medical focus from a familiar statewide brand.

Location & Hours:

• 9521 S Orange Blossom Trail #107, Orlando, Florida 32837
• Open Monday–Saturday 9am–8:45pm; Sunday 10am–8pm
• Medical (Florida medical marijuana card required)

Curaleaf – Orlando International Drive serves medical patients right in the heart of Orlando’s tourist corridor. Despite its proximity to attractions, the shop operates like a calm medical clinic, with a clean, minimalist layout and straightforward check-in process. Patients often appreciate the predictable Curaleaf menu, which echoes what you’ll find at the brand’s other Florida locations and shows up frequently in Herb’s dispensary listings and product roundups. For adults who work in the nearby hospitality industry, extended evening hours make it easier to swing by after a long shift.

Curaleaf leans on medically focused branding and standardized extraction processes, which is reassuring if you care about consistent dosing from batch to batch. The International Drive location also highlights regular deals on flower, pre-rolls, and vapes, which you can spot in Herb’s directory or via Curaleaf’s own menu tools. While the vibe is not as boutique as some shops on this list, it’s efficient and accessible for both seasoned patients and cautious newcomers.

What Makes Them Special:

• Tourist-corridor convenience: Located on International Drive, making it accessible for patients staying or working in nearby hotels
• Standardized product lines: Consistent formulations across Florida help patients stick with what works
• Steady promotions: Frequent sales and loyalty rewards that pair well with Herb’s deals tracking
• Accessible setup: ADA-friendly entrance, on-site ATM, and clear signage

Best For: Medical patients who value reliability and want an easy stop near Orlando’s attractions without sacrificing clinical professionalism.

Location & Hours:

• 6600 International Drive, Orlando, Florida 32819
• Open Monday–Saturday 9am–8:30pm; Sunday 10am–7pm
• Medical (Florida medical marijuana card required)

Jungle Boys – Orlando brings one of the country’s most talked-about cultivation brands to Central Florida’s medical market. The Orlando shop combines the company’s legacy grower reputation with a clean, contemporary storefront on University Boulevard. Patients who already follow Jungle Boys through Herb’s strain features or social media will recognize the emphasis on in-house genetics and carefully dialed-in cultivation. Even if you’re not chasing specific strain names, the staff are used to explaining terpene profiles in plain language so you can match products to your comfort level.

Because this is a medical-only market, the atmosphere is more subdued than a recreational flagship, but you still feel the brand’s culture in the merchandising and menu choices. Longtime patients often use this shop to explore small-batch or limited releases while relying on staple strains for day-to-day relief. The location also serves a large student and residential population, which means they’re used to working with a wide range of age-appropriate adult patients and experience levels.

What Makes Them Special:

• Cultivation-first reputation: Emphasis on in-house flower genetics that already have a national following
• Strain education: Staff comfortable talking terpenes, effects, and aroma in accessible terms
• Rotating drops: More limited releases than you might see at purely corporate chains
• Herb-friendly footprint: Frequently appears in Herb’s coverage of standout Florida dispensaries and flower brands

Best For: Adult medical patients who already care about strain nuance or want to explore more connoisseur-level flower within Florida’s regulated program.

Location & Hours:

• 11401 University Blvd, Orlando, Florida 32817
• Open Monday–Saturday 8:30am–8:30pm; Sunday 10am–6pm
• Medical (Florida medical marijuana card required)

MÜV Dispensary Orlando – Garland sits downtown, making it a convenient stop for city-center residents and workers. The store leans into a modern, pharmacy-adjacent aesthetic with clean lines, digital menus, and clearly labeled product categories. MÜV’s statewide reputation for topicals and advanced formulations (like transdermal patches) gives patients more options beyond inhalable products, which Herb’s guides often spotlight when discussing alternative delivery methods. The Garland Avenue location feels compact but efficient, keeping wait times manageable even during busy periods.

Because it’s centrally located, this MÜV shop often becomes the go-to for professionals who want a quick, discreet visit during lunch breaks or after work. Staff are used to answering practical questions about onset time and duration in a medical context without veering into hype. The dispensary’s menu typically includes everything from standard flower to more specialized formulations, which show up in MÜV’s brand presence across Herb’s Florida pages.

What Makes Them Special:

• Downtown accessibility: Easy to reach from offices, apartments, and public transit in central Orlando
• Broad product formats: Known for innovative topicals and patches alongside more traditional options
• Streamlined experience: Digital menus and a compact floorplan keep visits efficient
• Consistent statewide brand: Patients who like MÜV can find similar offerings at other Florida locations listed on Herb

Best For: Adults who work or live downtown and want a quick, medically focused stop with more than just inhalable cannabis options.

Location & Hours:

• 101 S Garland Ave, Suite 110, Orlando, Florida 32801
• Open Monday–Saturday 9am–7pm; Sunday 11am
• Medical (Florida medical marijuana card required)

Sunnyside Medical Cannabis Dispensary Orlando – West anchors the west side of the city along West Colonial Drive. The design is bright and welcoming, with Sunnyside’s signature clean branding and large windows that make the space feel more like a modern wellness store than a traditional dispensary. This location’s menu reflects the brand’s multi-state presence, with house lines plus select partner brands that often show up in Herb’s reviews and strain guides. Because it serves a mix of long-time locals and commuters heading in and out of downtown, the shop tends to keep steady traffic throughout the day.

Sunnyside staff emphasize conversation over rushed transactions, which can help newer patients ease into asking more detailed questions. The store’s layout makes it easy to see different product categories at a glance, from tinctures to vapes to capsules. Combined with regular promotions that align with Sunnyside’s broader Florida footprint, the Orlando – West location is one of the more approachable “first-visit” dispensaries in Herb’s local listings.

What Makes Them Special:

• Welcoming design: Bright, modern interior that feels more like a wellness boutique than a clinic
• Balanced menu: Mix of Sunnyside house brands and carefully selected partner products
• West-side convenience: Handy for patients living or working along the West Colonial corridor
• Education-forward staff: Patient consultants ready to walk through options at a comfortable pace

Best For: Adults who want a friendly, non-intimidating first experience at a medical dispensary on Orlando’s west side.

Location & Hours:

• 6990 W Colonial Dr, Orlando, Florida 32818
• Open Monday–Saturday 9am–8:30pm; Sunday 9am–7pm
• Medical (Florida medical marijuana card required)

Fluent – Orlando sits on North Orange Avenue and leans into a polished, almost spa-like atmosphere. The brand focuses heavily on clear labeling and simple product lines, which can be helpful if you’re overwhelmed by overly busy menus elsewhere. Fluent’s Orlando dispensary typically carries a balanced mix of flower, vapes, tinctures, and capsules, as well as more specialized formulations that show up across Herb’s Florida product coverage. The check-in process is orderly, with staff guiding patients step-by-step through ID and registry verification in a medical context.

Because it’s close to several popular neighborhoods, this location often functions as a “neighborhood shop” for repeat patients who appreciate familiar faces behind the counter. Fluent’s statewide loyalty program and regular discount days give budget-conscious adults predictable ways to save without chasing promo codes. The combination of professional design, clear information, and a stable menu makes this a solid middle-ground option between boutique and big-box-style dispensaries.

What Makes Them Special:

• Clean, clinical aesthetic: Minimalist design that reinforces a medical, not party, atmosphere
• Easy-to-understand product lines: Clear naming and labeling reduce confusion for newer patients
• Neighborhood feel: Many repeat customers see the same staff on each visit
• Herb visibility: Frequently appears in Herb’s lists of Florida dispensaries with consistent patient feedback

Best For: Adult patients who appreciate a calm, organized environment and straightforward menu without too many overlapping product lines.

Location & Hours:

• 1901 N Orange Ave, Orlando, Florida 32804
• Open daily around 9am–8:30pm
• Medical (Florida medical marijuana card required)

Cannabist Orlando brings a national brand with a “higher standard” tagline to the east side of Orlando. The shop sits along East Colonial Drive and focuses on a streamlined, modern interior that still feels approachable rather than overly corporate. Cannabist emphasizes service and product knowledge, training staff to talk calmly about different formats, potencies, and ingredient sourcing in a medical context. As a result, many adult patients use this store as a go-to spot for asking detailed questions about new product types they’ve discovered through Herb’s educational content.

Because Cannabist operates multiple Florida locations, the Orlando shop benefits from a broader supply chain and curated menu. Patients can expect a range of flower, vapes, concentrates, edibles, and wellness-oriented products, plus periodic promotions that align with the company’s statewide calendar. The East Colonial Drive address also makes this dispensary a convenient option for patients coming from surrounding suburbs or the University of Central Florida area.

What Makes Them Special:

• Service-forward reputation: Staff focused on patient guidance and thoughtful recommendations
• Strong statewide presence: Part of a larger Florida network that helps stabilize supply
• East-side convenience: Positioned on a major corridor that’s easy to reach from multiple neighborhoods
• Consistent with Herb’s brand partners: Often appears in Herb’s directory and broader Florida coverage

Best For: Adult medical patients on the east side of Orlando who want a modern, service-oriented dispensary experience with a broad menu.

Location & Hours:

• 10615 East Colonial Drive, Orlando, Florida 32817
• Open daily 8am–8:45pm
• Medical (Florida medical marijuana card required)

While not as flashy as some newer brands, VidaCann – Orlando has quietly built a loyal patient base from its North Semoran Boulevard location. The shop emphasizes a wellness-first environment, with staff who are comfortable talking through product categories in clear, non-technical language. VidaCann’s menu leans on steady, reliable options rather than constant limited drops, which many patients appreciate when they find something that works and want to stick with it. The store’s location makes it accessible to adults coming from Baldwin Park, Winter Park, and several nearby residential areas.

VidaCann also partners with well-known cultivation brands, which you’ll often see cross-referenced in Herb’s Florida coverage. Inside, the vibe is unhurried, and staff typically give patients time to think through decisions instead of pushing upsells. For adults who prioritize discretion and steadiness over hype, this Orlando dispensary checks a lot of boxes.

What Makes Them Special:

• Wellness-forward environment: Focus on calm, patient conversations rather than flashy decor
• Reliable product lineup: Emphasis on staples that remain in stock across visits
• Convenient for nearby neighborhoods: Easy access from Semoran-adjacent communities and major roads
• Integrated with Herb’s ecosystem: Appears in Herb’s Orlando directory and broader Florida dispensary listings

Best For: Adult patients seeking a steady, low-drama shop where they can find familiar products and talk through options at an unhurried pace.

Location & Hours:

• 1700 N Semoran Blvd, Suite 160, Orlando, Florida 32807
• Open Monday–Friday 10am-7pm, Saturday 10am-5pm, Sunday 11am-4pm
• Medical (Florida medical marijuana card required)

Trulieve’s presence on the east side of Orlando includes a busy location along Colonial Drive often referred to as Trulieve – Orlando Colonial, which you’ll also see reflected in Herb’s Orlando listings. This store serves a wide catchment area of adult patients from east Orlando, including those who work or study near the University corridor. The interior design follows Trulieve’s standard medical model: check-in area, consultation counters, and clearly labeled product displays. Because many patients treat this as their primary east-side dispensary, staff become familiar with regulars’ preferences and can suggest products within the same medical framework.

The Colonial location typically carries the same broad menu as other Trulieve stores, including flower, vapes, concentrates, and ingestible products. Adults who already rely on Trulieve’s formulations at other Florida stores featured on Herb often choose this shop to avoid long cross-town drives. It’s not an experiential destination, but it is a practical, high-throughput MMTC designed around helping registered patients refill their medicine efficiently.

What Makes Them Special:

• High-volume east-side location: Ideal for patients who live or work along the Colonial corridor
• Predictable Trulieve menu: Similar offerings to other Trulieve stores across the state
• Familiar workflow: Standardized check-in and consultation process streamline each visit
• Strong integration with Herb: Listed among Trulieve’s Orlando locations on Herb’s dispensaries page

Best For: Adult medical patients who already trust Trulieve products and want a convenient east Orlando option.

Location & Hours:

• 11291 E Colonial Dr Orlando, FL 32817
• Open Monday–Saturday 9am–8:45pm; Sunday 9am–8:30pm
• Medical (Florida medical marijuana card required)

Rounding out Orlando’s Trulieve footprint is a location commonly known as Trulieve – Orlando Millenia, serving adults near the Mall at Millenia and surrounding retail district. This shop offers the same core product lines as other Trulieve dispensaries, providing continuity for patients who need stable, repeatable medicine across multiple locations featured on Herb. The Millenia-area storefront combines a modern reception area with clinical back-of-house operations, reinforcing that you’re in a medical setting even though you’re near one of Orlando’s busiest shopping zones. Many adults who work in the area appreciate being able to combine errands with a medical dispensary stop in a single trip.

Because of its proximity to major roads and shopping centers, the Millenia location tends to see a steady flow of after-work visits. Staff are used to working with both long-term patients and adults who recently joined Florida’s medical program and are still figuring out which formulations fit their needs. For many Orlando residents, this shop offers the most convenient way to maintain continuity of care with Trulieve products while staying within the city’s southern retail district.

What Makes Them Special:

• Millenia retail hub access: Convenient for adults who already shop or work near the Mall at Millenia
• Standardized Trulieve experience: Same workflows, packaging, and labeling as other Trulieve locations on Herb
• Steady after-work traffic: Staff used to efficiently serving patients during peak evening hours
• Part of a broader network: One of several Orlando Trulieve shops listed on Herb, making it easy to switch locations if you move across town

Best For: Adult Trulieve patients who live or work near the Millenia retail area and want a familiar medical dispensary experience close by.

Location & Hours:

• 4192 Conroy Rd, Ste 111, Orlando, FL 32839
• Open Monday–Saturday 9am–8:45pm; Sunday 10am–8pm
• Medical (Florida medical marijuana card required)