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CBD for Schizophrenia Shows Promise: Study

There’s been mixed findings on whether cannabis can be an antipsychotic. Now, new research out of Brazil finds that at least one cannabinoid—CBD for schizophrenia—could be an effective treatment.

Aug 19, 2018 - Rob Hoffman

Rear view of woman looking out to city through window ( Photo by d3sign via Getty Images)

Rear view of woman looking out to city through window ( Photo by d3sign via Getty Images)

In Brazil, new research on rodents is showing potential for cannabis as a treatment for schizophrenia.

This study comes from the University of São Paulo, where researchers conducted a study into whether cannabidiol (CBD)—a non-psychoactive cannabinoid found in cannabis—could potentially be used as a treatment for schizophrenia

Current research on cannabis for schizophrenia is limited, and often contradictory. Some researchers have written, for example, that adult psychosis patients (in this case, people 25-years-old or older) who are lifetime cannabis consumers appear to “exhibit superior cognition compared to never-using patients.” However, they claim the reverse is true for patients under the age of 25.

Study CBD is suggested to be effective for treating schizophrenia01 Two Men Weighed Cannabis on an NYPD Squad Car in Brooklyn—and Police Found the Video
Photo by Ivan De Dousa/Eye Em via Getty Images

The research that does exist suggests that different compounds in cannabis—like THC and CBD—may have widely varying potentials as either a treatment, or trigger, for schizophrenia. One 2017 study, for example, suggests that CBD for schizophrenia has antipsychotic properties that are beneficial for patients. But the previous year, other researchers conducted an animal study that suggested an association between THC consumption during adolescence and the formation of psychotic disorders like schizophrenia.

In other words, it’s still uncertain whether cannabis can be used to treat schizophrenia, and if it can, whether this only applies to specific cannabinoids like CBD. But at the very least, this recent study suggests more research is warranted.

This recent experiment was done to assess the potential of CBD for schizophrenia among patients in “Peri-adolescence,” meaning children between the ages of about 8 and 11. The researcher performed the trial on rats who showed abnormal behaviors associated with schizophrenia. They were then treated with CBD for between 30 to 60 days.

These findings are currently in their pre-publication stage, with the researchers preparing to publish their full data soon.


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