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Claudia Barbosa

Guides | 03.04.2023

The Best Cannabinoids For Stress

Forget strains. Here are the cannabinoids that can help you kick stress to the curb.

Most cannabis users will often look for different strains to experience different effects. While this can work, there’s more of a prominent difference between cannabinoids than between cannabis strains.

Although strains can contain different cannabinoids, we suggest looking into products that emphasize one particular cannabinoid, like CBD or Delta-8 THC. This will help you feel the effects of that cannabinoid stronger, meaning you can easily tell if it works for your situation or not. 

Below, we’ve included the top five cannabinoids that help with stress. Read on to learn more about how you can kick stress to the curb.


CBD (cannabidiol) is a natural compound found in the hemp plant. The major difference between CBD and other cannabinoids is that it’s non-psychoactive, meaning it doesn’t produce euphoria or feelings of being high.

Instead, it can regulate the body’s stress response and decrease cortisol levels, the main hormone that’s released when we feel stressed out. It’s an excellent tool for relaxation and general well-being that’s praised in the medical community.


Similar to CBD, CBN is a naturally occurring cannabinoid found in the hemp plant. It’s also non-psychoactive, meaning there won’t be any feelings of being high. 

Although, the main difference between CBD and CBN is that the latter produces sleepier effects, making it ideal for end-of-day use. It’s another praised cannabinoid in the medical community that’s celebrated for its stress-reducing and anxiety-reliving effects, especially when it’s time to hit the hay.


Here’s where the cannabinoids start to get psychoactive. HHC is another naturally occurring cannabinoid that’s found in trace amounts within cannabis and hemp plants. It does produce mild feelings of euphoria and feeling “high,” but on a much smaller scale than Delta-8 and Delta-9 THC. 

HHC is a great cannabinoid for relaxation. Its mildly intoxicating effects provide feelings of mood elevation and optimism, so it’s perfect for beating stress throughout the day. It may also help reduce anxiety and symptoms of depression, which is greatly needed in times of stress.

Delta-8 THC

Another mildly psychoactive cannabinoid from hemp and cannabis is Delta-8 THC. It’s a naturally occurring cannabinoid that produces feelings of mild euphoria, clearheadedness, and mood elevation, the perfect combination for stress relief. 

However, it’s worth noting that the psychoactive effects of Delta-8 THC are stronger than HHC and milder than Delta-9 THC. So, it’s the perfect mid-way point for consumers looking for more of a clear-headed high than Delta-9, but still promotes the deep relaxation provided by other cannabinoids like HHC, CBD, and CBN. 

Delta-9 THC

Last but certainly not least, we have tried and true, classic Delta-9 THC. This is the primary psychoactive cannabinoid found in cannabis and hemp plants. Although it can decrease stress in seasoned users, high doses of Delta-9 THC in beginners may cause anxiety.

Still, if used properly with your own tolerance, Delta-9 THC can do wonders for stress relief, anxiety, and depression. Its euphoric and uplifting effects help promote optimism and peace of mind, making it an excellent choice for experienced users looking to manage their stress levels. 

Final Thoughts

Various plant properties can help reduce stress. While some consumers choose to beat stress while experimenting with different strains, we encourage you to explore the benefits of different cannabinoids to help find something that works for your specific situation. The cannabinoids on this list are a great start.

Herbworthy: PAX Era


Melissa Jaramillo

Herbworthy: Gary Peyton Feminized Seeds By OG Seeds


Melissa Jaramillo


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