β-Caryophyllene’s Effects on Anxiety & Depression

β-caryophyllene is present in oils of various plants including rosemary, hops & black pepper. German researchers discovered that it's also a cannabinoid, meaning it can affect anxiety & depression.

• It doesn't get you high

  By The Stoner's Cookbook

  First and foremost, β-caryophyllene specifically targets the CB2 receptor, which doesn't produce a high. However, it still affects anxiety & depression, and could be useful for medicinal uses.

• From the lab

  By The Stoner's Cookbook

  “The present study has clearly demonstrated the anxiolytic and anti-depressant effect of β-caryophyllene and its underlying mechanism in a CB2 receptor-dependent manner in rodents” – UAE University 

• CB2 receptors & anxiety

  By The Stoner's Cookbook

  Studies have shown that CB2 receptors can reduce anxiety & depression. As mentioned before, β-Caryophyllene only targets CB2—not only does it keep anxiety from getting worse, it makes it better.

• CB1 receptors & anxiety

  By The Stoner's Cookbook

  Cannabinoids that target CB1 receptors can help with anxiety at low doses, but high doses seem to make things worse. β-Caryophyllene only targets CB2, so it doesn't contribute to anxiety.

• Something we Already Knew

  By The Stoner's Cookbook

  One of the most common self-reported reasons that people use cannabis is to releive stress, tension in anxiety. In a way this study scientifically backs what many of us knew to be common knowledge.